Second-guess，是个较为常见的英文动词，它具有两种含义，且彼此关联不大。
首先，Second-guess可以表示：事后对某人的行为、或某个事件进行批评；质疑最初的想法、行为（to criticize someone’s actions or an event after it has happened; To be unsure/rethinking your first opinion or thought or idea.）。例如：Of course it’s easy to second-guess the management of the election campaign, but I do think serious mistakes were made.（事后对竞选活动的管理挑毛病似乎很容易，但我确实认为犯了严重的错误。）又如：She added that Americans who voted for Trump may soon end up second- guessing their decision.（她补充说，那些给特朗普投票的选民可能很快就开始怀疑自己当初的决定了。）
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其次，second-guess还有“猜测、预测、揣度”（to guess what someone will do in the future）的意思。参考例句：It’s tough to second-guess alien motivations. Often SETI scientists have assumed that extraterrestrials who have survived long enough to make contact will have overcome any warlike traits they had earlier in their evolution.（很难揣度外星人的意图。通常，SETI的科学家们会认为那些能长存到与人类接触的外星人，早已在进化中克服了好战的特质）。
参考链接：
https://answers.yahoo.com/question/index?qid=20080317205217AAnQQRu